Multidimensional Scaling (MDS) Plots

MDS plot by Breed and Feed.Efficiency

Differential abundance modelling in limma

Differential abundance analyses were conducted using limma-voom.

Compare abundance within each Breed and across Breed with each Feed.Efficiency

Analyses of abundance used the formula ~Breed + Feed.Efficiency in limma.

Output includes the columns:

  • logFC: log2 fold change, with the group listed first in the comparison or file name being the numerator of the fold change
  • AveExpr: Average expression across all samples
  • P.Value: Raw p-value from the test that the log fold change differs from 0
  • adj.P.Val: Benjamini-Hochberg false discovery rate adjusted p-value
Top 200 genes for Feed Efficiency main effect
Number of genes with adjusted P < 0.05 = 23
Output file is FeedEfficiency_main_effect.txt
logFC AveExpr t P.Value adj.P.Val B
Cellulosilyticum sp. WCF-2 5.09591 4.94789 8.58129 0.00000 0.00000 14.91978
Lactobacillus johnsonii 4.00813 4.96636 7.08050 0.00000 0.00001 10.14329
Desulfitobacterium metallireducens 2.69173 2.38917 5.36389 0.00000 0.00195 4.66526
Enterococcus faecalis 3.48412 7.23520 4.99153 0.00001 0.00524 3.52307
Clostridium fermenticellae 3.20971 4.61490 4.69166 0.00002 0.00943 2.56288
Clostridium taeniosporum 3.12825 5.20173 4.68207 0.00002 0.00943 2.53937
Brevibacillus choshinensis 2.27830 2.15080 4.65053 0.00003 0.00943 2.46452
Tsukamurella paurometabola 2.45462 2.30774 4.46251 0.00005 0.01538 1.89849
Cutibacterium avidum 3.13119 3.21850 4.27190 0.00009 0.02547 1.33437
Streptomyces chartreusis 2.68424 2.37196 4.22291 0.00011 0.02685 1.19228
Paenibacillus uliginis 1.97342 2.09937 4.10635 0.00016 0.03142 0.85452
Sphaerochaeta coccoides 2.60299 3.26193 4.09390 0.00016 0.03142 0.82218
Sedimentibacter sp. zth1 2.49920 5.61093 4.07486 0.00017 0.03142 0.76793
Bacillus subtilis 4.08999 3.88015 4.06879 0.00018 0.03142 0.73683
Desulfosporosinus meridiei 2.87515 3.41133 3.98937 0.00023 0.03522 0.52678
Enterocloster clostridioformis 0.34839 10.98071 3.97447 0.00024 0.03522 -0.26249
Sporosarcina ureae 2.58435 2.70636 3.96562 0.00024 0.03522 0.45905
Blautia hansenii 0.64784 9.46411 3.95323 0.00025 0.03522 0.05470
Sutcliffiella horikoshii 2.52461 3.04577 3.90010 0.00030 0.03941 0.27752
Roseburia hominis 0.52650 11.58969 3.84401 0.00036 0.04427 -0.85120
Brevibacillus brevis 3.17076 4.24447 3.83066 0.00037 0.04427 0.08727
[Clostridium] scindens 0.33211 10.95487 3.80441 0.00040 0.04460 -0.76096
Staphylococcus pseudoxylosus 3.86042 4.84534 3.79884 0.00041 0.04460 -0.01226
Prochlorococcus marinus 3.17095 5.20111 3.73671 0.00050 0.05176 -0.17020
Paenibacillus sp. FSL R7-0331 2.57075 5.33991 3.70892 0.00054 0.05313 -0.24661
Blautia sp. LZLJ-3 0.44633 9.37062 3.70209 0.00055 0.05313 -0.66678
Paenibacillus sp. FSL R7-0273 2.10421 6.01943 3.68182 0.00059 0.05341 -0.33386
Enterococcus cecorum 2.96594 4.12326 3.67608 0.00060 0.05341 -0.33779
Gardnerella vaginalis 2.65973 3.08688 3.65488 0.00064 0.05500 -0.39390
Pantoea dispersa 2.20139 2.44789 3.62066 0.00071 0.05614 -0.49616
Bifidobacterium angulatum 2.83966 5.33439 3.61820 0.00072 0.05614 -0.48788
Clostridium isatidis 2.46812 5.88253 3.61565 0.00072 0.05614 -0.50844
Rossellomorea marisflavi 2.56711 5.52201 3.57935 0.00080 0.06074 -0.59308
Syntrophotalea carbinolica 2.15662 2.57308 3.54299 0.00090 0.06575 -0.69684
Anaerobutyricum hallii 0.47736 10.90675 3.52201 0.00095 0.06778 -1.56386
Petrocella atlantisensis 1.83864 6.36479 3.51142 0.00099 0.06778 -0.79667
Anaerostipes caccae 0.37509 9.12840 3.50441 0.00101 0.06778 -1.17720
Clostridium argentinense 1.82888 6.45104 3.49559 0.00103 0.06778 -0.84462
Fusobacterium mortiferum 1.60327 1.85620 3.45903 0.00115 0.07361 -0.94650
Clostridium formicaceticum 2.85312 3.77255 3.43115 0.00125 0.07649 -0.98648
Burkholderia cenocepacia 2.03766 2.07433 3.42912 0.00126 0.07649 -1.02321
Pseudomonas entomophila -1.27085 1.53482 -3.41299 0.00132 0.07760 -1.14143
Niallia circulans 2.69965 4.40856 3.40373 0.00136 0.07760 -1.03821
Sphaerochaeta globosa 2.29657 4.94611 3.39035 0.00141 0.07760 -1.07843
Bacillus paralicheniformis 2.07484 4.39465 3.38647 0.00143 0.07760 -1.13236
Anaerocolumna chitinilytica 0.50754 8.67315 3.38508 0.00143 0.07760 -1.42144
Coprococcus catus 0.42435 10.49161 3.37380 0.00148 0.07837 -1.86016
Bdellovibrio bacteriovorus 2.39648 3.45686 3.36717 0.00151 0.07837 -1.14284
Caldanaerobacter subterraneus 1.72057 2.32467 3.33648 0.00165 0.08306 -1.25405
Paenibacillus borealis 2.43668 3.40161 3.33326 0.00167 0.08306 -1.23182
[Ruminococcus] torques 0.45029 10.22678 3.30152 0.00183 0.08826 -1.98545
Paenibacillus beijingensis 2.37863 3.39381 3.29879 0.00184 0.08826 -1.30891
Clostridium sp. SY8519 0.46524 12.08630 3.26738 0.00202 0.09482 -2.68865
Paenibacillus lycopersici 1.45315 6.41878 3.24106 0.00217 0.10020 -1.50836
Lactobacillus crispatus 1.91435 3.92146 3.23527 0.00221 0.10020 -1.52190
Sporolactobacillus terrae 2.31113 3.34435 3.22572 0.00227 0.10037 -1.49195
Citrifermentans bremense 2.55296 4.15222 3.21726 0.00233 0.10037 -1.51396
Lachnoclostridium phytofermentans 0.57020 8.58529 3.21076 0.00237 0.10037 -1.87111
Longicatena caecimuris 1.65007 6.95008 3.18072 0.00258 0.10037 -1.72184
Paenibacillus donghaensis 2.07511 5.53904 3.17721 0.00261 0.10037 -1.63535
Parvimonas micra 2.20737 6.60717 3.17554 0.00262 0.10037 -1.69433
Anaerostipes hadrus 0.69575 10.14222 3.17301 0.00264 0.10037 -2.31040
Biomaibacter acetigenes 1.85810 5.68080 3.16973 0.00266 0.10037 -1.64545
Baekduia soli 1.88276 2.73506 3.14889 0.00283 0.10037 -1.71281
Bradyrhizobium diazoefficiens 3.23974 5.31055 3.14604 0.00285 0.10037 -1.72191
Hathewaya histolytica 2.18908 5.72694 3.12858 0.00299 0.10037 -1.75102
Ilumatobacter coccineus -0.43213 0.97350 -3.11366 0.00312 0.10037 -2.29604
Bifidobacterium catenulatum 2.70932 5.04818 3.10908 0.00316 0.10037 -1.79138
Clostridium tyrobutyricum 2.15864 5.25759 3.10378 0.00321 0.10037 -1.79790
Clostridium sp. DL-VIII 2.66226 5.01878 3.08955 0.00334 0.10037 -1.82584
Caldalkalibacillus thermarum 2.44529 3.17206 3.07832 0.00345 0.10037 -1.88929
Marinobacter fonticola -0.43520 0.97684 -3.07331 0.00350 0.10037 -2.39740
Actinobaculum sp. 313 -0.43615 0.97788 -3.06103 0.00362 0.10037 -2.42809
Flexistipes sinusarabici -0.43615 0.97788 -3.06103 0.00362 0.10037 -2.42809
Sphingomonas sp. YZ-8 -0.43615 0.97788 -3.06103 0.00362 0.10037 -2.42809
Serratia marcescens 2.62904 7.00686 3.05768 0.00365 0.10037 -2.02608
Methylacidiphilum sp. IT6 -0.43706 0.97888 -3.04932 0.00374 0.10037 -2.45727
Roseobacter ponti -0.43706 0.97888 -3.04932 0.00374 0.10037 -2.45727
Hyphomicrobium sp. MC1 -0.43706 0.97888 -3.04932 0.00374 0.10037 -2.45727
Staphylococcus xylosus 2.78215 3.28560 3.04787 0.00375 0.10037 -1.95175
Actinomyces sp. oral taxon 414 1.52459 1.76722 3.04622 0.00377 0.10037 -2.01954
Ichthyobacterium seriolicida -0.44226 0.97350 -3.03938 0.00384 0.10037 -2.48747
Veillonella rodentium 1.61255 6.74803 3.03407 0.00390 0.10037 -2.08267
Listeria monocytogenes 2.98154 3.85513 3.03263 0.00391 0.10037 -1.96046
Breznakiella homolactica 1.82349 5.82963 3.03258 0.00391 0.10037 -1.98851
Usitatibacter palustris -0.63471 1.09617 -3.02835 0.00396 0.10037 -2.38925
Deinococcus gobiensis -0.43879 0.98079 -3.02742 0.00397 0.10037 -2.51163
Sulfurospirillum halorespirans -0.43879 0.98079 -3.02742 0.00397 0.10037 -2.51163
Skermania piniformis -0.43879 0.98079 -3.02742 0.00397 0.10037 -2.51163
Dissulfurispira thermophila -0.43879 0.98079 -3.02742 0.00397 0.10037 -2.51163
Xanthomonas albilineans -0.43879 0.98079 -3.02742 0.00397 0.10037 -2.51163
Algoriphagus sanaruensis -0.44333 0.97465 -3.02626 0.00398 0.10037 -2.51991
Deinococcus deserti -0.43960 0.98170 -3.01712 0.00409 0.10037 -2.53711
Thermoanaerobacterium sp. RBIITD 2.03802 3.09966 3.01545 0.00410 0.10037 -2.02025
Paenibacillus cellulosilyticus 2.11580 2.92012 3.01291 0.00413 0.10037 -2.03280
Nocardioides baekrokdamisoli -0.44039 0.98258 -3.00723 0.00420 0.10037 -2.56151
Pukyongia salina -0.44527 0.97684 -3.00172 0.00426 0.10037 -2.58033
Trichormus azollae -0.70546 1.09283 -2.99869 0.00430 0.10037 -2.46699
Helicobacter sp. NHP19-0012 -0.44115 0.98344 -2.99773 0.00431 0.10037 -2.58489
Ureibacillus thermosphaericus 2.21439 4.97786 2.99672 0.00432 0.10037 -2.12441
Levilactobacillus koreensis -0.64625 1.10425 -2.99578 0.00433 0.10037 -2.46574
Veillonella parvula 2.62558 3.48519 2.99308 0.00437 0.10037 -2.07342
Cyclobacterium amurskyense -0.44441 0.97985 -2.99138 0.00439 0.10037 -2.60391
Corynebacterium cystitidis -0.53900 1.10191 -2.98964 0.00441 0.10037 -2.53216
Amycolatopsis sp. DSM 110486 1.47342 1.98181 2.98322 0.00449 0.10037 -2.15006
Lachnoclostridium sp. YL32 0.32987 10.81698 2.98008 0.00452 0.10037 -2.99882
Myxococcus sp. SCHIC003 -0.44261 0.98509 -2.97979 0.00453 0.10037 -2.62888
Kordia antarctica -0.44705 0.97888 -2.97945 0.00453 0.10037 -2.63485
Geobacter pickeringii 2.19824 4.37064 2.97423 0.00460 0.10037 -2.09489
Pseudooceanicola algae -0.44333 0.98588 -2.97127 0.00463 0.10037 -2.64967
Hymenobacter sp. DG25B -2.30909 5.18920 -2.96711 0.00469 0.10037 -2.13554
Lentzea guizhouensis 1.64754 2.18488 2.96355 0.00473 0.10037 -2.17199
Calothrix sp. PCC 7716 -0.44402 0.98665 -2.96305 0.00474 0.10037 -2.66969
Undibacterium sp. KW1 -0.44402 0.98665 -2.96305 0.00474 0.10037 -2.66969
Psychrobacter sanguinis -0.44668 0.98258 -2.96227 0.00475 0.10037 -2.67501
Gramella salexigens -0.44869 0.98079 -2.95913 0.00479 0.10037 -2.68437
Tepidimonas taiwanensis -0.44470 0.98740 -2.95509 0.00484 0.10037 -2.68901
Sulfitobacter sp. JK7-1 -0.44470 0.98740 -2.95509 0.00484 0.10037 -2.68901
Lactobacillus iners 2.71324 3.84306 2.95406 0.00486 0.10037 -2.14722
Corynebacterium gerontici -0.44738 0.98344 -2.95333 0.00487 0.10037 -2.69675
Owenweeksia hongkongensis -0.44945 0.98170 -2.94957 0.00492 0.10037 -2.70759
Pseudomonas multiresinivorans -0.44535 0.98813 -2.94735 0.00495 0.10037 -2.70779
Pandoraea norimbergensis -0.65896 1.11485 -2.94707 0.00495 0.10037 -2.57964
Methylomicrobium sp. wino1 -0.44598 0.98885 -2.93983 0.00505 0.10073 -2.72597
Aureimonas sp. SA4125 -0.44598 0.98885 -2.93983 0.00505 0.10073 -2.72597
Clostridium sp. AWRP 1.74426 2.23545 2.92794 0.00522 0.10146 -2.25281
Frateuria aurantia -0.44719 0.99023 -2.92551 0.00525 0.10146 -2.76053
Arcobacter sp. FWKO B -0.45003 0.98665 -2.92069 0.00532 0.10146 -2.77555
Sphingomonas sp. AK-PDB1-5 -0.44777 0.99090 -2.91868 0.00535 0.10146 -2.77698
Atlantibacter hermannii -0.67034 1.12359 -2.91601 0.00539 0.10146 -2.65076
Flavobacterium sp. M31R6 -0.45229 0.98509 -2.91495 0.00540 0.10146 -2.79117
Herbinix luporum 0.41444 9.22897 2.91404 0.00542 0.10146 -2.75658
Acetobacterium sp. KB-1 1.96245 4.56155 2.91382 0.00542 0.10146 -2.26904
Nonlabens sp. Ci31 -0.45296 0.98588 -2.90705 0.00552 0.10146 -2.81008
Streptococcus porcinus -0.45130 0.98813 -2.90577 0.00554 0.10146 -2.81131
Methanobrevibacter millerae -0.93902 13.12587 -2.89473 0.00571 0.10146 -4.29663
Aequorivita sp. H23M31 -0.67660 1.12332 -2.89346 0.00573 0.10146 -2.70528
Nocardia wallacei -0.44998 0.99343 -2.89326 0.00573 0.10146 -2.83789
Bacillus pumilus 1.60221 7.26374 2.88983 0.00578 0.10146 -2.46164
Paeniglutamicibacter sp. Y32M11 -0.45050 0.99403 -2.88735 0.00582 0.10146 -2.85198
Flavobacterium psychrophilum -0.45486 0.98813 -2.88487 0.00586 0.10146 -2.86298
Anaerocolumna cellulosilytica 0.49252 8.25753 2.88466 0.00587 0.10146 -2.63903
Limosilactobacillus pontis -0.46665 0.97788 -2.88267 0.00590 0.10146 -2.87708
Finegoldia magna 1.42186 7.36582 2.88233 0.00590 0.10146 -2.48314
Pseudogulbenkiania sp. NH8B -0.68114 1.13225 -2.88059 0.00593 0.10146 -2.73164
Acidipropionibacterium virtanenii -0.54681 1.13040 -2.87901 0.00596 0.10146 -2.79330
Gluconobacter oxydans -0.86606 1.29222 -2.87732 0.00598 0.10146 -2.62432
Paenibacillus sp. BIHB4019 2.16071 3.67316 2.87151 0.00608 0.10236 -2.36694
Selenomonas sp. oral taxon 136 1.51915 7.69513 2.86492 0.00619 0.10288 -2.57439
Salegentibacter salegens -0.45657 0.99023 -2.86463 0.00619 0.10288 -2.91101
Nitrospirillum amazonense 1.68579 3.67804 2.85826 0.00630 0.10363 -2.42542
Echinicola soli -0.88274 1.13842 -2.85502 0.00635 0.10363 -2.78945
Aeromonas simiae 1.33522 1.70597 2.85106 0.00642 0.10363 -2.49950
Blautia argi 0.37081 9.71152 2.84987 0.00644 0.10363 -3.02408
Marinobacter salarius -0.45381 0.99793 -2.84970 0.00644 0.10363 -2.94132
Agromyces sp. G127AT -0.45424 0.99845 -2.84482 0.00653 0.10364 -2.95284
Treponema sp. OMZ 838 -0.45509 0.99946 -2.83524 0.00670 0.10364 -2.97537
Azotobacter chroococcum -0.45509 0.99946 -2.83524 0.00670 0.10364 -2.97537
Gillisia sp. Hel1_33_143 -0.45915 0.99343 -2.83473 0.00671 0.10364 -2.98143
Sutterella faecalis 2.10686 4.62966 2.83389 0.00672 0.10364 -2.42202
Luteimonas sp. MC1750 -0.45550 0.99996 -2.83061 0.00678 0.10364 -2.98625
Flavobacterium anhuiense -0.45964 0.99403 -2.82925 0.00681 0.10364 -2.99429
Cylindrospermum stagnale -0.42560 0.97465 -2.82886 0.00681 0.10364 -3.01083
Blautia obeum 0.33388 11.67041 2.82798 0.00683 0.10364 -3.66385
Pantoea agglomerans 2.37322 3.09487 2.82480 0.00689 0.10364 -2.46075
Agromyces aureus -0.45629 1.00092 -2.82163 0.00695 0.10364 -3.00729
Bacillus weihaiensis -0.42002 0.98258 -2.82074 0.00696 0.10364 -3.02232
Pseudomonas salegens -0.48940 0.97577 -2.81706 0.00703 0.10364 -3.03940
Simplicispira suum -0.45959 0.99741 -2.81579 0.00705 0.10364 -3.02426
Flavobacterium sp. CS20 -0.46120 0.99577 -2.81303 0.00711 0.10364 -3.03227
Phreatobacter sp. NMCR1094 -0.46005 0.99793 -2.81095 0.00715 0.10364 -3.03559
Burkholderia sp. DHOD12 -0.45743 1.00231 -2.80884 0.00719 0.10364 -3.03715
Sinorhizobium meliloti 2.55065 3.21688 2.80852 0.00719 0.10364 -2.48516
Clostridium cellulovorans 1.29222 6.95390 2.80350 0.00729 0.10443 -2.61819
Suicoccus acidiformans -0.45816 1.00320 -2.80074 0.00734 0.10450 -3.05602
Flavobacterium sp. 140616W15 -0.46265 0.99741 -2.79798 0.00740 0.10450 -3.06733
Paraburkholderia caribensis -0.45851 1.00363 -2.79680 0.00742 0.10450 -3.06517
Flavobacterium pallidum -1.68744 2.20114 -2.79449 0.00746 0.10455 -2.57674
Exiguobacterium alkaliphilum -0.45921 1.00448 -2.78908 0.00757 0.10477 -3.08307
Collimonas arenae -0.56083 1.13980 -2.78732 0.00761 0.10477 -3.01038
Fischerella sp. NIES-4106 -2.03196 5.75253 -2.78688 0.00762 0.10477 -2.59795
Azospirillum oryzae -0.45954 1.00490 -2.78530 0.00765 0.10477 -3.09181
Enterobacter cloacae 3.25391 5.37115 2.77885 0.00778 0.10553 -2.56973
Arthrobacter woluwensis -0.46020 1.00572 -2.77796 0.00780 0.10553 -3.10879
Myroides phaeus -0.46488 0.99996 -2.77487 0.00786 0.10553 -3.12085
Pseudobutyrivibrio xylanivorans 0.53501 11.46873 2.77366 0.00789 0.10553 -3.73238
Dysgonomonas sp. HDW5A -0.72468 1.15817 -2.77143 0.00793 0.10553 -2.97603
Burkholderia multivorans -1.03514 1.35418 -2.76752 0.00802 0.10553 -2.84618
Oceanihabitans sp. IOP_32 -0.46115 1.00691 -2.76740 0.00802 0.10553 -3.13312
Cellulophaga sp. HaHaR_3_176 -0.46571 1.00092 -2.76625 0.00804 0.10553 -3.14072
Cupriavidus oxalaticus -0.42476 0.98813 -2.76172 0.00814 0.10624 -3.15881
Flavobacterium sp. KK2020170 -0.46652 1.00185 -2.75799 0.00822 0.10643 -3.15972
Alkaliphilus metalliredigens 1.86761 2.60215 2.75711 0.00824 0.10643 -2.61272
Microbacterium sp. 4R-513 -0.46265 1.00879 -2.75094 0.00837 0.10706 -3.17090
Burkholderia dolosa -0.46265 1.00879 -2.75094 0.00837 0.10706 -3.17090
Sphingomonas sp. AAP5 -0.46293 1.00915 -2.74780 0.00844 0.10739 -3.17808
Streptomyces sp. ZYC-3 -0.46404 1.01055 -2.73573 0.00871 0.10891 -3.20564
Desulfuromonas versatilis 1.80552 5.15237 2.73426 0.00875 0.10891 -2.67387
Pseudonocardia sp. CGMCC 4.1532 -0.46457 1.01123 -2.72996 0.00885 0.10891 -3.21877
Nonlabens spongiae -0.73582 1.16756 -2.72911 0.00887 0.10891 -3.06821
Top 200 genes for CHAR Breed main effect
Number of genes with adjusted P < 0.05 = 16
Output file is CHAR_main_effect.txt
logFC AveExpr t P.Value adj.P.Val B
Staphylococcus sp. 11-B-312 7.81553 4.11096 9.29439 0.00000 0.00000 17.32478
Corynebacterium flavescens -3.63936 2.13879 -6.66401 0.00000 0.00003 8.79595
Corynebacterium freneyi 2.55085 6.71645 5.63100 0.00000 0.00077 5.49305
Lactobacillus crispatus -3.87064 3.92146 -5.21989 0.00000 0.00240 4.17763
Bacillus licheniformis 6.49225 5.21920 5.14757 0.00000 0.00246 4.00119
Conexibacter woesei -3.82153 4.88710 -4.82209 0.00001 0.00619 2.93022
Prosthecochloris sp. GSB1 -3.20168 3.03820 -4.68684 0.00002 0.00836 2.56873
Staphylococcus condimenti 3.05188 5.95329 4.60431 0.00003 0.00962 2.27396
Thermobispora bispora -3.28226 2.73604 -4.45361 0.00005 0.01408 1.86538
Staphylococcus saprophyticus 3.79718 5.78894 4.34861 0.00007 0.01608 1.53045
Helcococcus kunzii -3.54223 4.06632 -4.34477 0.00007 0.01608 1.54921
Rhodococcus rhodochrous -4.29511 3.53603 -4.32484 0.00008 0.01608 1.49078
Limosilactobacillus vaginalis -3.29656 2.32785 -4.27048 0.00009 0.01771 1.32971
Desulfosporosinus acidiphilus -3.24645 3.00612 -4.24553 0.00010 0.01783 1.25786
Minicystis rosea -3.36429 4.97906 -4.20905 0.00011 0.01872 1.12926
Streptomyces sp. NHF165 -3.69896 3.53127 -3.95134 0.00026 0.03986 0.41667
Propionibacterium australiense -3.05778 3.24053 -3.83786 0.00036 0.05348 0.10433
Clostridium gasigenes -3.14154 5.77020 -3.78082 0.00044 0.06026 -0.04852
Jeotgalibaca porci -1.91380 1.57839 -3.70426 0.00055 0.07222 -0.26930
Saccharomonospora viridis 0.93174 9.85327 3.63478 0.00068 0.08477 -1.79480
Clostridium septicum -3.32721 4.85979 -3.59809 0.00076 0.09020 -0.53925
Methanosarcina mazei 2.93487 2.07093 3.57082 0.00082 0.09347 -0.61499
Desulfovibrio sp. 86 -3.19758 5.37299 -3.55157 0.00087 0.09473 -0.65683
Desulfovibrio gigas -2.72708 5.69121 -3.53712 0.00091 0.09480 -0.69278
Acetobacterium sp. KB-1 -2.83606 4.56155 -3.52111 0.00096 0.09547 -0.74325
Thermomonospora curvata -2.58025 2.66638 -3.47502 0.00110 0.10127 -0.87283
Lactiplantibacillus plantarum -2.16628 1.69345 -3.47317 0.00110 0.10127 -0.87917
Methanobrevibacter millerae 1.67617 13.12587 3.46320 0.00114 0.10127 -2.51913
Caldanaerobacter subterraneus -2.20388 2.32467 -3.44707 0.00119 0.10256 -0.94333
Nostoc sp. NIES-4103 2.09021 1.86367 3.37082 0.00149 0.12407 -1.16607
Homo sapiens 0.72686 11.66051 3.35672 0.00156 0.12511 -2.19908
Dictyoglomus thermophilum 1.35330 1.23663 3.31787 0.00174 0.13218 -1.35531
Methanosarcina barkeri 1.30266 1.23096 3.31637 0.00175 0.13218 -1.36234
Lentilactobacillus buchneri -1.65646 1.54072 -3.28940 0.00189 0.13673 -1.36229
Moorella glycerini -2.19054 5.93452 -3.28065 0.00194 0.13673 -1.35405
Calothrix parasitica 1.79477 7.82576 3.26792 0.00201 0.13673 -1.52123
Corynebacterium jeikeium 2.84549 2.29683 3.26507 0.00203 0.13673 -1.40739
Fischerella sp. NIES-4106 3.27459 5.75253 3.25130 0.00211 0.13851 -1.41709
Denitrobacterium detoxificans -0.45402 10.05854 -3.21133 0.00237 0.15133 -2.12449
Pradoshia sp. D12 -1.79291 1.75966 -3.19592 0.00247 0.15353 -1.59071
Xanthomonas translucens -4.32410 6.04694 -3.18871 0.00252 0.15353 -1.63026
Butyrivibrio proteoclasticus -0.60343 11.26410 -3.16699 0.00269 0.15941 -2.53324
Ferribacterium limneticum -1.69226 6.81993 -3.14618 0.00285 0.16514 -1.71853
Peptoniphilus harei -2.63243 5.86734 -3.10362 0.00321 0.18193 -1.78397
Treponema caldarium -2.04398 2.64416 -3.08527 0.00338 0.18727 -1.87607
Lacipirellula parvula 1.01326 1.22252 3.07020 0.00353 0.18803 -2.01857
Bacillus paralicheniformis 2.32197 4.39465 3.06825 0.00354 0.18803 -1.90692
Flavobacterium alkalisoli 1.03879 1.23496 3.05296 0.00370 0.19211 -2.05436
Chryseobacterium indologenes 3.55407 5.31647 3.02849 0.00396 0.20142 -1.96390
Xanthomonas oryzae 1.15532 1.28397 2.98912 0.00441 0.22004 -2.18601
Lancefieldella parvula -1.47845 6.96450 -2.93930 0.00506 0.22159 -2.24618
Granulicatella adiacens 1.22433 1.29523 2.93019 0.00518 0.22159 -2.32363
Scytonema sp. NIES-4073 1.71831 1.74082 2.92411 0.00527 0.22159 -2.29568
Rhodocaloribacter litoris -1.47060 6.78933 -2.91917 0.00534 0.22159 -2.26100
Thermoanaerobacterium sp. RBIITD -2.27605 3.09966 -2.91402 0.00542 0.22159 -2.25799
Kutzneria albida -2.25843 2.89062 -2.90742 0.00552 0.22159 -2.29024
Allosaccharopolyspora coralli -2.25143 2.60047 -2.90026 0.00562 0.22159 -2.29547
Corynebacterium aurimucosum 0.58295 6.56733 2.88954 0.00579 0.22159 -2.80660
Cereibacter sphaeroides -2.85097 7.22898 -2.85959 0.00627 0.22159 -2.40116
Methanofervidicoccus sp. A16 0.96102 1.10434 2.84761 0.00648 0.22159 -2.62329
Campylobacter lari 1.25015 1.17797 2.83967 0.00662 0.22159 -2.58369
Bifidobacterium subtile -2.63572 4.39389 -2.82346 0.00691 0.22159 -2.43035
Aminomonas paucivorans -2.51026 4.16765 -2.80278 0.00730 0.22159 -2.46899
Neobacillus mesonae 0.94478 1.11345 2.80183 0.00732 0.22159 -2.72472
Tessaracoccus timonensis 1.77907 1.62563 2.79944 0.00737 0.22159 -2.55489
Clavibacter michiganensis -2.93913 7.75226 -2.78888 0.00758 0.22159 -2.63173
Vallitalea guaymasensis -2.11794 6.08919 -2.77703 0.00782 0.22159 -2.57940
Caloranaerobacter azorensis -2.43587 4.03737 -2.77505 0.00786 0.22159 -2.54665
Bos taurus 0.58783 12.25561 2.76082 0.00816 0.22159 -3.97586
Luteithermobacter gelatinilyticus 0.88011 1.10920 2.75601 0.00826 0.22159 -2.83426
Paludibacterium paludis -1.23652 1.38932 -2.75487 0.00829 0.22159 -2.68375
Caulifigura coniformis -1.61722 1.73350 -2.75003 0.00839 0.22159 -2.68354
Treponema brennaborense -1.17715 7.22999 -2.73760 0.00867 0.22159 -2.72690
Microbulbifer thermotolerans 0.73715 1.09832 2.73726 0.00868 0.22159 -2.94829
Sphaerochaeta coccoides -2.03739 3.26193 -2.72855 0.00888 0.22159 -2.68657
Microbulbifer sp. GL-2 0.72849 1.10614 2.71259 0.00926 0.22159 -2.99479
Brasilonema sennae 0.73259 1.10807 2.70701 0.00939 0.22159 -3.00505
Bifidobacterium eulemuris -2.34515 3.78591 -2.69730 0.00963 0.22159 -2.73472
Agarilytica rhodophyticola 0.77894 1.11156 2.69577 0.00967 0.22159 -3.02627
Limosilactobacillus reuteri -2.58331 5.52504 -2.69468 0.00970 0.22159 -2.74894
Plesiomonas shigelloides 0.74784 1.11193 2.69175 0.00977 0.22159 -3.03505
Paenibacillus lutimineralis -1.66134 2.10699 -2.68745 0.00988 0.22159 -2.78483
Oligella urethralis 0.76542 1.11560 2.68185 0.01003 0.22159 -3.05287
Photobacterium profundum 0.75801 1.11946 2.67132 0.01030 0.22159 -3.07188
Corynebacterium nuruki 2.49671 2.78191 2.66965 0.01035 0.22159 -2.74650
Fusobacterium varium 1.79982 2.02050 2.66649 0.01043 0.22159 -2.82330
Vallitalea pronyensis -2.28816 5.12459 -2.66448 0.01049 0.22159 -2.78053
Costertonia aggregata -1.96118 2.20641 -2.66266 0.01054 0.22159 -2.85814
Flavobacterium magnum 2.65398 2.67400 2.65901 0.01064 0.22159 -2.81178
Mahella australiensis -2.70398 4.66005 -2.65160 0.01084 0.22159 -2.81496
Nocardia arthritidis 0.78561 1.12815 2.64623 0.01099 0.22159 -3.11769
Leptotrichia trevisanii 0.81700 1.13299 2.63683 0.01126 0.22159 -3.13295
Ornithinimicrobium sp. HY006 0.81747 1.14204 2.61271 0.01198 0.22159 -3.17659
Morganella morganii -1.99734 7.22015 -2.61267 0.01198 0.22159 -2.99043
Symbiobacterium thermophilum -0.49567 7.80988 -2.59647 0.01248 0.22159 -3.16075
Chryseobacterium camelliae 2.74030 3.33579 2.59444 0.01255 0.22159 -2.93856
Bordetella avium 0.86040 1.15264 2.59025 0.01268 0.22159 -3.21500
Cardiobacterium sp. Marseille-Q4385 1.22142 1.49522 2.58768 0.01277 0.22159 -3.09912
Limosilactobacillus fermentum -2.29645 6.10582 -2.58174 0.01296 0.22159 -3.03368
Methanobrevibacter smithii 0.89663 11.51566 2.57907 0.01305 0.22159 -4.13902
Ruminococcus bicirculans -0.58300 11.62077 -2.57160 0.01330 0.22159 -4.18723
Bifidobacterium lemurum -2.16658 5.83315 -2.54694 0.01415 0.22159 -3.03730
Cupriavidus taiwanensis -1.99185 7.13296 -2.54593 0.01419 0.22159 -3.11031
Filifactor alocis -2.08358 6.47110 -2.54589 0.01419 0.22159 -3.08057
Pseudomonas fluorescens 0.38474 9.34494 2.54101 0.01436 0.22159 -3.58690
Shewanella khirikhana 0.94410 1.18299 2.53550 0.01456 0.22159 -3.30626
Ruminococcus champanellensis -0.47145 11.87900 -2.53499 0.01458 0.22159 -4.34115
Nostoc linckia 1.28118 1.37322 2.53232 0.01468 0.22159 -3.25153
Acetivibrio thermocellus -0.77455 8.06275 -2.52424 0.01498 0.22159 -3.38518
Gordonia sp. YC-JH1 0.91782 1.18774 2.52403 0.01499 0.22159 -3.32694
Saccharibacillus brassicae -0.36471 7.54755 -2.50537 0.01570 0.22159 -3.35043
Clostridium sp. SY8519 -0.40861 12.08630 -2.50412 0.01575 0.22159 -4.59631
Anabaena sp. YBS01 3.47854 11.67686 2.50347 0.01578 0.22159 -4.03064
Mariniflexile sp. TRM1-10 0.48744 0.97577 2.49972 0.01592 0.22159 -3.66536
Enterococcus rotai 0.53197 0.97229 2.49610 0.01607 0.22159 -3.67715
Streptococcus pantholopis 0.53197 0.97229 2.49610 0.01607 0.22159 -3.67715
Hyphomonas sp. Mor2 0.48845 0.97684 2.49453 0.01613 0.22159 -3.67561
Streptomyces sp. TLI_053 0.95580 1.20415 2.49392 0.01616 0.22159 -3.37752
Faecalibacillus intestinalis -1.44329 1.54870 -2.49220 0.01622 0.22159 -3.22963
Ottowia sp. 27C 0.47966 0.97985 2.49188 0.01624 0.22159 -3.67824
Vibrio europaeus 0.52340 0.97350 2.49147 0.01625 0.22159 -3.68605
Mariprofundus ferrinatatus 0.52340 0.97350 2.49147 0.01625 0.22159 -3.68605
Rubrobacter indicoceani 0.52340 0.97350 2.49147 0.01625 0.22159 -3.68605
Nostoc carneum 3.03413 7.91403 2.48988 0.01632 0.22159 -3.29040
Arthrobacter sp. NicSoilB8 0.97204 1.20953 2.48934 0.01634 0.22159 -3.38279
Desulfotalea psychrophila 0.49029 0.97788 2.48875 0.01636 0.22159 -3.68721
Marinobacterium aestuarii 0.52542 0.97465 2.48549 0.01650 0.22159 -3.69797
Hydrocarboniclastica marina 0.52542 0.97465 2.48549 0.01650 0.22159 -3.69797
Streptococcus chenjunshii 0.52542 0.97465 2.48549 0.01650 0.22159 -3.69797
Sarcina sp. JB2 -2.45291 5.64165 -2.48439 0.01654 0.22159 -3.17615
Nostoc sp. MS1 0.53624 0.97465 2.48406 0.01656 0.22159 -3.70111
Bombilactobacillus bombi 0.49632 0.97788 2.48341 0.01658 0.22159 -3.69896
Thermomonas carbonis 0.49632 0.97788 2.48341 0.01658 0.22159 -3.69896
Muricauda ruestringensis 0.49203 0.97888 2.48314 0.01659 0.22159 -3.69849
Microbulbifer sp. ALW1 0.52732 0.97577 2.47954 0.01674 0.22159 -3.70982
Pseudomonas asturiensis 0.52732 0.97577 2.47954 0.01674 0.22159 -3.70982
Paenibacillus sp. FSL R7-0273 -1.76715 6.01943 -2.47786 0.01681 0.22159 -3.22327
Vagococcus carniphilus 1.19055 1.39511 2.47747 0.01683 0.22159 -3.52098
Fluviibacter phosphoraccumulans 0.49461 0.97985 2.47689 0.01685 0.22159 -3.71122
Cytobacillus kochii 0.48414 0.98258 2.47607 0.01689 0.22159 -3.71002
Scardovia inopinata 0.52911 0.97684 2.47371 0.01699 0.22159 -3.72142
CrAssphage sp. 0.54001 0.97684 2.47244 0.01704 0.22159 -3.72420
Pseudomonas alkylphenolica 0.53083 0.97788 2.46814 0.01722 0.22159 -3.73247
Ferrimonas balearica 0.53083 0.97788 2.46814 0.01722 0.22159 -3.73247
Lentilactobacillus parabuchneri 0.50139 0.98079 2.46740 0.01725 0.22159 -3.73106
Shewanella yunxiaonensis 0.50139 0.98079 2.46740 0.01725 0.22159 -3.73106
Zophobihabitans entericus 0.50139 0.98079 2.46740 0.01725 0.22159 -3.73106
Oceanicoccus sagamiensis 0.54177 0.97788 2.46695 0.01727 0.22159 -3.73509
Dyella sp. M7H15-1 0.49836 0.98258 2.46243 0.01746 0.22159 -3.73988
Spartinivicinus ruber 0.49930 0.98258 2.46164 0.01750 0.22159 -3.74161
Staphylococcus felis 0.54341 0.97888 2.46158 0.01750 0.22159 -3.74575
Mycoplasma sp. Mirounga ES2806-NAS 0.54341 0.97888 2.46158 0.01750 0.22159 -3.74575
Bacillus aquiflavi 1.35535 1.51025 2.46105 0.01752 0.22159 -3.32249
Aromatoleum aromaticum 0.48857 0.98509 2.46080 0.01754 0.22159 -3.74019
Pseudomonas coronafaciens 0.57723 0.98079 2.45333 0.01786 0.22159 -3.76178
Enterococcus cecorum -2.26855 4.12326 -2.45282 0.01788 0.22159 -3.29192
Kushneria marisflavi 0.50607 0.98344 2.45253 0.01790 0.22159 -3.76038
Alkalihalobacillus halodurans 0.50128 0.98428 2.45240 0.01790 0.22159 -3.75957
Chloroflexus aggregans 0.53539 0.98079 2.45239 0.01790 0.22159 -3.76383
Luteibacter pinisoli 0.50223 0.98428 2.45163 0.01794 0.22159 -3.76124
Salinibacterium hongtaonis 0.49137 0.98665 2.45141 0.01795 0.22159 -3.75864
Gilliamella apicola 0.54644 0.98079 2.45137 0.01795 0.22159 -3.76605
Desulfuromonas sp. AOP6 -2.37594 4.28642 -2.45022 0.01800 0.22159 -3.22265
Methanobrevibacter arboriphilus 1.07626 9.07037 2.45000 0.01801 0.22159 -3.75235
Shewanella pealeana 0.50752 0.98428 2.44759 0.01812 0.22159 -3.77005
Maribius sp. THAF1 0.50752 0.98428 2.44759 0.01812 0.22159 -3.77005
Thauera hydrothermalis 0.50266 0.98509 2.44756 0.01812 0.22159 -3.76906
Sphingosinicella sp. BN140058 0.50266 0.98509 2.44756 0.01812 0.22159 -3.76906
Oleiphilus messinensis 0.53679 0.98170 2.44754 0.01812 0.22159 -3.77347
Tomitella sp. HY188 0.49272 0.98740 2.44696 0.01814 0.22159 -3.76736
Gramella fulva 0.50361 0.98509 2.44680 0.01815 0.22159 -3.77071
Methanococcoides methylutens 0.54786 0.98170 2.44656 0.01816 0.22159 -3.77558
Yersinia aldovae 0.50893 0.98509 2.44281 0.01833 0.22159 -3.77936
Paenibacillus baekrokdamisoli 0.54934 0.98258 2.44176 0.01838 0.22159 -3.78489
Dongshaea marina 0.53961 0.98344 2.43786 0.01855 0.22159 -3.79225
Acidovorax monticola 0.50626 0.98665 2.43762 0.01856 0.22159 -3.78859
Enterobacter sp. RHBSTW-00994 0.50626 0.98665 2.43762 0.01856 0.22159 -3.78859
Devriesea agamarum 0.50626 0.98665 2.43762 0.01856 0.22159 -3.78859
Thermobifida fusca -0.93014 9.31599 -2.43587 0.01864 0.22159 -4.21802
Herbaspirillum huttiense 0.50657 0.98740 2.43400 0.01873 0.22159 -3.79547
Rhodanobacter glycinis 0.50657 0.98740 2.43400 0.01873 0.22159 -3.79547
Brachyspira murdochii 0.57224 0.98428 2.43321 0.01877 0.22159 -3.80123
Nissabacter sp. SGAir0207 0.54091 0.98428 2.43304 0.01877 0.22159 -3.80161
Roseburia hominis -0.38420 11.58969 -2.43157 0.01884 0.22159 -4.55634
Ruminococcus albus -1.14854 13.88548 -2.43020 0.01890 0.22159 -5.58263
Mannheimia granulomatis 0.50780 0.98813 2.42977 0.01892 0.22159 -3.80366
Bergeyella cardium 0.50780 0.98813 2.42977 0.01892 0.22159 -3.80366
Halomonas elongata 0.51291 0.98740 2.42945 0.01894 0.22159 -3.80530
Yersinia aleksiciae 0.51291 0.98740 2.42945 0.01894 0.22159 -3.80530
Bacillus pseudomycoides 0.57359 0.98509 2.42871 0.01897 0.22159 -3.80992
Psychrobacter sp. YP14 0.50998 0.98885 2.42497 0.01915 0.22159 -3.81311
Corynebacterium endometrii 0.54339 0.98588 2.42387 0.01920 0.22159 -3.81933
Maribacter sp. MJ134 0.51018 0.98955 2.42172 0.01930 0.22159 -3.81923
Myroides odoratus 0.51660 0.98955 2.41735 0.01951 0.22159 -3.82863
Haemophilus influenzae 0.51660 0.98955 2.41735 0.01951 0.22159 -3.82863
Mycetocola zhujimingii 0.51660 0.98955 2.41735 0.01951 0.22159 -3.82863
Pseudopuniceibacterium antarcticum 0.51244 0.99090 2.41415 0.01966 0.22159 -3.83381
Nostoc flagelliforme 0.51343 0.99090 2.41346 0.01969 0.22159 -3.83528
Ralstonia insidiosa 0.50349 0.99343 2.41248 0.01974 0.22159 -3.83420
Staphylococcus chromogenes 0.57856 0.98813 2.41213 0.01976 0.22159 -3.84168
Top 200 genes for HYB main effect
Number of genes with adjusted P < 0.05 = 121
Output file is HYB_main_effect.txt
logFC AveExpr t P.Value adj.P.Val B
Corynebacterium aurimucosum -8.38042 6.56733 -42.38812 0.00000 0.00000 76.83000
Corynebacterium freneyi -7.61842 6.71645 -14.35730 0.00000 0.00000 32.83230
Corynebacterium stationis -7.11243 6.49583 -12.57555 0.00000 0.00000 27.83064
Caldibacillus thermoamylovorans -6.18923 5.64777 -10.73774 0.00000 0.00000 22.35806
Novibacillus thermophilus -5.09420 5.65586 -9.41509 0.00000 0.00000 18.05385
Staphylococcus condimenti -6.08798 5.95329 -8.59991 0.00000 0.00000 15.54532
Lactobacillus crispatus -4.94941 3.92146 -7.79107 0.00000 0.00000 12.83223
Burkholderia gladioli 5.71050 3.89378 7.17994 0.00000 0.00000 10.76449
Corynebacterium flavescens -3.86368 2.13879 -7.10257 0.00000 0.00000 10.50696
Corynebacterium xerosis -4.86838 8.13817 -6.62196 0.00000 0.00001 8.88008
Thermoactinomyces vulgaris -4.79925 9.86313 -6.25978 0.00000 0.00002 7.57528
Asticcacaulis excentricus 3.22643 1.92943 6.20293 0.00000 0.00002 7.47287
Ureibacillus thermosphaericus -5.10936 4.97786 -6.19988 0.00000 0.00002 7.44375
Lactobacillus delbrueckii -1.54113 10.14264 -6.00052 0.00000 0.00005 6.31644
Butyrivibrio hungatei 1.78296 11.37777 5.61737 0.00000 0.00016 4.47555
Limosilactobacillus vaginalis -3.97003 2.32785 -5.59773 0.00000 0.00016 5.43279
Alkalihalobacillus clausii -4.91678 7.34944 -5.40539 0.00000 0.00028 4.81803
Xanthomonas campestris 3.76964 2.33595 5.40458 0.00000 0.00028 4.81384
Aeribacillus pallidus -3.90238 3.26262 -5.28800 0.00000 0.00040 4.42967
Mycolicibacterium thermoresistibile -5.04513 4.35587 -5.24518 0.00000 0.00044 4.24106
Thermobifida fusca -3.91357 9.31599 -5.22619 0.00000 0.00045 4.02488
Lactobacillus johnsonii -3.22587 4.96636 -5.15333 0.00000 0.00055 3.94482
Saccharomonospora viridis -6.37040 9.85327 -5.11047 0.00001 0.00061 3.77740
Brevilactibacter sp. MC1595 3.67863 2.54559 4.90416 0.00001 0.00117 3.19621
Streptomyces bingchenggensis 4.64079 3.05658 4.86121 0.00001 0.00130 3.05199
Syntrophobacter fumaroxidans 3.26022 2.30199 4.84807 0.00001 0.00131 3.01286
Desulfolutivibrio sulfoxidireducens 3.72736 3.73394 4.76070 0.00002 0.00169 2.75633
Leptolyngbya sp. 15MV 2.38589 1.66202 4.70743 0.00002 0.00195 2.55358
Enterocloster clostridioformis -0.49060 10.98071 -4.67960 0.00002 0.00207 1.56666
Corynebacterium striatum -4.10455 4.49323 -4.65669 0.00003 0.00216 2.36545
Limosilactobacillus mucosae -3.63448 10.52443 -4.62843 0.00003 0.00229 1.77077
Desulfonema limicola 2.95819 2.09220 4.57915 0.00003 0.00262 2.14943
Modestobacter marinus 2.41490 1.69911 4.50463 0.00004 0.00325 1.92499
Phycisphaera mikurensis 2.94972 2.34432 4.46192 0.00005 0.00357 1.80292
Variovorax paradoxus 4.27972 4.36740 4.45412 0.00005 0.00357 1.80373
Staphylococcus saprophyticus -4.48612 5.78894 -4.44944 0.00005 0.00357 1.69271
Akkermansia muciniphila 0.52269 8.86517 4.43696 0.00005 0.00362 1.31900
Ligilactobacillus ruminis -2.63866 9.71702 -4.39060 0.00006 0.00410 1.08807
Alistipes finegoldii 0.76366 9.86750 4.35748 0.00007 0.00445 0.84472
Blautia sp. LZLJ-3 -0.61820 9.37062 -4.24924 0.00010 0.00617 0.63004
Ereboglobus luteus 3.38303 4.32938 4.16778 0.00013 0.00766 0.95380
Jeotgalibaca porci -2.14401 1.57839 -4.16686 0.00013 0.00766 0.86968
Ureibacillus thermophilus -3.32946 3.56391 -4.11678 0.00015 0.00878 0.74422
Anaerolinea thermophila 3.72932 4.09527 4.10331 0.00016 0.00896 0.75988
Actinoplanes sp. N902-109 3.19682 2.47315 4.08773 0.00017 0.00920 0.65884
Desulfosediminicola ganghwensis 1.79588 1.46121 4.08067 0.00017 0.00921 0.59031
Clostridium sp. SY8519 -0.68401 12.08630 -4.07306 0.00017 0.00923 -0.77272
Nitrospirillum amazonense 3.16250 3.67804 4.06375 0.00018 0.00931 0.63237
Bacillus paralicheniformis -3.09647 4.39465 -4.04691 0.00019 0.00962 0.53434
Hymenobacter sp. PAMC 26554 3.25734 5.54717 4.01579 0.00021 0.01018 0.47306
Bifidobacterium pseudocatenulatum 0.61217 10.20860 4.01576 0.00021 0.01018 -0.32138
Lactobacillus amylovorus -4.48892 9.93894 -4.01034 0.00021 0.01018 0.02649
Treponema succinifaciens 0.70249 9.29759 3.99282 0.00022 0.01043 -0.17446
Lactobacillus helveticus -3.09523 2.37577 -3.99081 0.00023 0.01043 0.35355
Arthrobacter alpinus 2.20584 1.62859 3.97563 0.00024 0.01074 0.31093
Hymenobacter nivis 3.32083 5.39992 3.95969 0.00025 0.01098 0.28746
Fibrella sp. ES10-3-2-2 3.47716 3.65753 3.95726 0.00025 0.01098 0.34110
Chelatococcus sp. CO-6 -3.47968 2.58432 -3.95093 0.00026 0.01101 0.24687
Roseburia hominis -0.63069 11.58969 -3.93843 0.00027 0.01126 -0.99744
Lactiplantibacillus plantarum -2.42542 1.69345 -3.90443 0.00030 0.01231 0.11043
Syntrophus aciditrophicus 3.32366 2.87539 3.88331 0.00032 0.01294 0.06508
Persicimonas caeni 2.80541 5.01671 3.83127 0.00037 0.01497 -0.04673
Planctomyces sp. SH-PL62 3.69296 3.26336 3.81965 0.00039 0.01502 -0.08044
Rhodococcus rhodochrous -4.28873 3.53603 -3.81479 0.00039 0.01502 -0.11528
Lentilactobacillus buchneri -1.91060 1.54072 -3.81476 0.00039 0.01502 -0.16760
Kibdelosporangium phytohabitans 3.24566 2.87098 3.78507 0.00043 0.01596 -0.16778
Desulfovibrio vulgaris 2.68197 5.70851 3.78204 0.00043 0.01596 -0.22151
Pontibacillus sp. ALD_SL1 -3.37728 3.38570 -3.78068 0.00044 0.01596 -0.24085
Dialister hominis -6.92980 7.91726 -3.74216 0.00049 0.01771 -0.46954
Streptomyces sp. So13.3 2.53529 1.95644 3.70994 0.00054 0.01900 -0.43676
Fischerella sp. NIES-4106 3.54361 5.75253 3.70982 0.00054 0.01900 -0.40536
Veillonella rodentium -2.48253 6.74803 -3.70284 0.00055 0.01914 -0.53463
Caldanaerobacter subterraneus -2.36658 2.32467 -3.68989 0.00058 0.01957 -0.49325
Paenibacillus yonginensis 3.49621 2.99325 3.68667 0.00058 0.01957 -0.46301
Pseudomonas putida 0.55426 9.93932 3.68077 0.00059 0.01966 -1.24590
Dialister massiliensis -5.40422 8.05104 -3.66395 0.00062 0.02042 -0.66520
Xanthomonas translucens -5.02679 6.04694 -3.65529 0.00064 0.02051 -0.63377
Megasphaera stantonii -0.52758 10.04725 -3.65324 0.00064 0.02051 -1.32763
Pseudodesulfovibrio cashew 2.65600 5.10920 3.64735 0.00065 0.02051 -0.61488
Desulfovibrio piger 0.69774 8.56887 3.64552 0.00066 0.02051 -1.03476
Enterobacter hormaechei 2.56643 1.71667 3.62509 0.00070 0.02155 -0.70551
Alistipes shahii 0.63252 10.20869 3.61387 0.00072 0.02203 -1.51803
Megasphaera elsdenii -2.88351 12.57958 -3.59585 0.00076 0.02298 -2.12416
Atopobium sp. oral taxon 416 -0.75814 9.62848 -3.57274 0.00082 0.02434 -1.45849
Candidatus Desulfovibrio trichonymphae 2.68887 2.68924 3.56056 0.00085 0.02466 -0.76571
Opitutus terrae 3.19546 3.16130 3.56054 0.00085 0.02466 -0.77710
Helicobacter pylori 3.50033 4.16252 3.55633 0.00086 0.02469 -0.79460
Acidaminococcus fermentans -1.66614 11.42496 -3.55020 0.00088 0.02486 -2.00760
Clostridium sp. 'deep sea' 3.22786 3.35304 3.54491 0.00089 0.02498 -0.82015
Dialister pneumosintes -4.17979 6.12115 -3.54055 0.00090 0.02502 -0.92013
Pseudomonas oryzihabitans 2.11826 1.77855 3.52461 0.00095 0.02596 -0.96169
Frigoriglobus tundricola 2.90075 2.40944 3.52091 0.00096 0.02596 -0.91121
Coprococcus catus -0.52901 10.49161 -3.51511 0.00097 0.02613 -1.86096
Sphaerotilus natans 1.59883 1.39839 3.49024 0.00105 0.02784 -1.12904
Kaustia mangrovi 2.01649 1.78566 3.44582 0.00120 0.03142 -1.18294
Acholeplasma hippikon 2.10287 1.77990 3.42744 0.00126 0.03215 -1.22714
Butyrivibrio fibrisolvens 0.38344 13.25182 3.42602 0.00127 0.03215 -3.23809
Trueperella pyogenes 0.48244 9.33581 3.42502 0.00127 0.03215 -1.83201
Nostoc carneum 3.87279 7.91403 3.42415 0.00128 0.03215 -1.38715
Cupriavidus pauculus 2.63597 5.53976 3.41374 0.00132 0.03282 -1.27742
Coprococcus comes -0.48520 11.08054 -3.39970 0.00137 0.03319 -2.38258
Treponema azotonutricium 2.99484 4.82259 3.39808 0.00138 0.03319 -1.22453
Stieleria maiorica 2.03000 1.80484 3.39706 0.00138 0.03319 -1.31444
Pradoshia sp. D12 -1.92325 1.75966 -3.39652 0.00138 0.03319 -1.31688
Riemerella anatipestifer 2.08159 1.95076 3.36960 0.00150 0.03557 -1.39905
Lacunisphaera limnophila 2.57759 5.95676 3.34836 0.00159 0.03719 -1.44001
Agrobacterium vitis 2.57313 5.47786 3.34794 0.00160 0.03719 -1.44611
Alicycliphilus denitrificans 2.52881 2.04155 3.34087 0.00163 0.03761 -1.48882
Acidaminococcus intestini -1.56544 11.57142 -3.32744 0.00169 0.03875 -2.68628
Paludibacterium paludis -1.47873 1.38932 -3.31738 0.00174 0.03954 -1.59812
Thermobispora bispora -2.75557 2.73604 -3.30886 0.00179 0.04006 -1.47431
Hymenobacter sedentarius 2.41808 6.17518 3.30660 0.00180 0.04006 -1.58460
Alcaligenes faecalis 3.10973 3.11137 3.29028 0.00189 0.04163 -1.55193
Geobacter sp. SVR 2.57719 2.77593 3.28435 0.00192 0.04198 -1.53231
Oceanithermus profundus 2.54106 2.05367 3.26841 0.00201 0.04357 -1.63985
Aminipila terrae -0.45150 8.20674 -3.25553 0.00209 0.04482 -1.99589
Calothrix brevissima 3.04235 2.86847 3.22837 0.00225 0.04792 -1.76085
Desulfovibrio sulfodismutans 2.82224 3.21929 3.22628 0.00227 0.04792 -1.68510
Weizmannia coagulans -0.47432 7.91037 -3.21778 0.00232 0.04853 -2.06703
Butyrivibrio virus Arawn 1.44878 1.39714 3.21602 0.00234 0.04853 -1.86367
Candidatus Izimaplasma sp. HR1 2.17012 2.00951 3.20307 0.00242 0.04994 -1.77818
Dehalococcoides mccartyi -0.92931 9.68614 -3.19171 0.00250 0.05116 -2.52390
Nonomuraea coxensis 2.61101 2.28502 3.18816 0.00253 0.05126 -1.85379
Alistipes onderdonkii 0.63939 9.89098 3.16865 0.00267 0.05374 -2.64496
Bifidobacterium thermophilum -2.64089 8.15337 -3.15444 0.00278 0.05550 -2.21301
Mucilaginibacter ginsenosidivorax 2.37824 2.43932 3.14763 0.00284 0.05613 -1.95585
Moorea producens 2.21060 6.37892 3.12463 0.00303 0.05921 -2.05315
Roseomonas sp. 1318 2.30779 2.29450 3.12307 0.00304 0.05921 -2.01433
Mucilaginibacter mali 2.37757 5.70340 3.11607 0.00310 0.05992 -2.04012
Rhodobacter capsulatus 2.19363 1.84970 3.11242 0.00313 0.06007 -2.03512
Pelolinea submarina 3.04959 3.65403 3.10772 0.00317 0.06041 -1.97032
Humisphaera borealis 2.31192 5.31318 3.09523 0.00329 0.06190 -2.08019
Streptosporangium sp. 'caverna' 2.69003 2.39133 3.09283 0.00331 0.06190 -2.03652
Nonomuraea sp. ATCC 55076 2.77188 2.54579 3.08871 0.00335 0.06190 -2.07773
Streptosporangium roseum 2.75652 2.64213 3.08827 0.00335 0.06190 -2.06657
Faecalibacterium prausnitzii 0.34613 13.73920 3.07457 0.00348 0.06384 -4.48937
Staphylococcus simiae 1.98482 1.91048 3.06773 0.00355 0.06460 -2.17539
Dehalobacter restrictus 2.90126 5.22270 3.06183 0.00361 0.06519 -2.17605
Aneurinibacillus soli -3.17793 4.46505 -3.02956 0.00395 0.07079 -2.18617
Desulfoglaeba alkanexedens 1.82602 1.69910 3.01847 0.00407 0.07248 -2.29185
Tannerella forsythia 0.62831 9.28689 3.00372 0.00424 0.07495 -2.91408
Mammaliicoccus vitulinus 1.48915 1.47280 2.99739 0.00431 0.07570 -2.40794
Acholeplasma palmae 2.53261 2.59943 2.99500 0.00434 0.07570 -2.27687
Bacillus subtilis -3.54235 3.88015 -2.99165 0.00438 0.07587 -2.45352
Haliangium ochraceum 2.87973 3.78693 2.98629 0.00445 0.07647 -2.26732
Christensenella sp. Marseille-P3954 0.57142 10.64827 2.98229 0.00450 0.07678 -3.38616
Pyxidicoccus sp. SCPEA002 2.93479 3.54271 2.97806 0.00455 0.07709 -2.28508
Olsenella uli -0.74325 10.80541 -2.97404 0.00460 0.07709 -3.42590
Conexibacter sp. SYSU D00693 2.51073 2.21487 2.97343 0.00461 0.07709 -2.40129
Paenibacillus lutimineralis -1.84118 2.10699 -2.96816 0.00467 0.07725 -2.42322
Sorangium cellulosum 0.36358 8.76769 2.96779 0.00468 0.07725 -2.90769
Corynebacterium humireducens -1.97664 2.08667 -2.96511 0.00471 0.07731 -2.45907
Faecalibacillus intestinalis -1.70799 1.54870 -2.95703 0.00482 0.07798 -2.48575
Luteitalea pratensis 2.76122 3.56979 2.95508 0.00484 0.07798 -2.35117
Streptococcus equi 2.61521 5.34164 2.95311 0.00487 0.07798 -2.45490
Micrococcus luteus 3.73103 3.66412 2.95244 0.00488 0.07798 -2.40749
Bacteroides sp. M10 2.34894 7.17936 2.94642 0.00496 0.07877 -2.75688
Blautia obeum -0.41171 11.67041 -2.94231 0.00502 0.07895 -3.80276
Anaerostipes hadrus -0.75324 10.14222 -2.93882 0.00506 0.07895 -3.33524
Pusillimonas faecalis 0.35306 10.97662 2.93863 0.00507 0.07895 -3.58661
Vogesella sp. LIG4 1.72207 1.81121 2.92979 0.00519 0.08031 -2.55623
Aquisphaera giovannonii 2.15873 5.93497 2.92780 0.00522 0.08031 -2.56196
Pasteurella multocida -2.46733 2.53498 -2.91477 0.00541 0.08269 -2.56980
Desulfuromonas versatilis 2.25481 5.15237 2.90745 0.00552 0.08336 -2.54913
Bulleidia sp. zg-1006 -0.53267 8.18419 -2.90553 0.00554 0.08336 -2.90721
Runella slithyformis 2.47254 2.36088 2.90505 0.00555 0.08336 -2.56781
Rhizobacter gummiphilus 1.17062 1.35703 2.90268 0.00559 0.08340 -2.68634
Massilia sp. CCM 8941 1.28666 1.29704 2.88314 0.00589 0.08680 -2.76148
Klebsiella pneumoniae 3.86814 6.59068 2.88050 0.00593 0.08680 -2.97111
Komagataeibacter xylinus 1.32323 1.31789 2.87998 0.00594 0.08680 -2.75886
Caldilinea aerophila 2.07337 2.48782 2.87910 0.00595 0.08680 -2.59858
Hymenobacter sp. DG01 2.23513 6.05363 2.87465 0.00603 0.08734 -2.74446
Mycetocola sp. JXN-3 1.27084 1.30067 2.86911 0.00612 0.08764 -2.79402
Verrucomicrobium sp. GAS474 2.73372 3.18315 2.86906 0.00612 0.08764 -2.54973
Nonomuraea nitratireducens 2.75821 2.52008 2.86572 0.00617 0.08793 -2.65901
Mycoplasma yeatsii 1.29427 1.32036 2.86282 0.00622 0.08797 -2.79958
Bacillus smithii -1.92424 1.80905 -2.86134 0.00625 0.08797 -2.71765
Opitutus sp. GAS368 2.63964 4.35222 2.85923 0.00628 0.08797 -2.60625
Amycolatopsis sp. FDAARGOS 1241 1.69892 1.68709 2.85657 0.00633 0.08798 -2.71744
Mageeibacillus indolicus 1.23211 9.25909 2.85395 0.00637 0.08798 -3.29512
Cellulosilyticum sp. WCF-2 -1.92825 4.94789 -2.85188 0.00641 0.08798 -2.83395
Desulfarculus baarsii 2.68079 5.54514 2.85087 0.00642 0.08798 -2.70172
Salinibacterium sp. ZJ450 1.19895 1.28171 2.84501 0.00652 0.08841 -2.86304
Defluviicoccus vanus -1.35741 1.32559 -2.84497 0.00653 0.08841 -2.83543
Fibrobacter succinogenes 2.53498 11.07897 2.83481 0.00671 0.09036 -3.86556
Actinoplanes friuliensis 1.64117 1.67551 2.82532 0.00688 0.09198 -2.79550
Ruminococcus albus -1.06312 13.88548 -2.82320 0.00692 0.09198 -5.35375
Streptococcus sobrinus 1.07159 1.22285 2.82211 0.00694 0.09198 -2.95579
Xanthobacter sp. YN2 2.76692 2.75914 2.81651 0.00704 0.09261 -2.71085
Rossellomorea vietnamensis -1.12846 1.24674 -2.81412 0.00709 0.09261 -2.95450
Pseudomonas fluorescens 0.41357 9.34494 2.81361 0.00710 0.09261 -3.39783
Thiolapillus brandeum 1.05264 1.22177 2.80811 0.00720 0.09348 -2.99047
Enterococcus mundtii -1.08617 1.22790 -2.80385 0.00728 0.09406 -2.99172
Bacteroides salyersiae 0.62754 9.68711 2.79828 0.00739 0.09497 -3.54481
Labrys sp. KNU-23 2.62085 2.61494 2.79117 0.00753 0.09628 -2.83939
Nitrogeniibacter mangrovi 1.05070 1.23396 2.78813 0.00759 0.09656 -3.02966
Clostridioides difficile 0.76980 11.70332 2.78492 0.00766 0.09689 -4.22198
Anabaena sp. YBS01 3.71638 11.67686 2.78270 0.00770 0.09697 -3.86196
Bordetella bronchialis 1.90920 2.01412 2.78018 0.00775 0.09712 -2.90811
Pseudopedobacter saltans 1.15351 1.25786 2.77577 0.00784 0.09777 -3.03669

R session information

## R version 4.0.1 (2020-06-06)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 16.04.6 LTS
## 
## Matrix products: default
## BLAS/LAPACK: /usr/lib/libopenblasp-r0.2.18.so
## 
## locale:
##  [1] LC_CTYPE=en_US       LC_NUMERIC=C         LC_TIME=en_US       
##  [4] LC_COLLATE=en_US     LC_MONETARY=en_US    LC_MESSAGES=en_US   
##  [7] LC_PAPER=en_US       LC_NAME=C            LC_ADDRESS=C        
## [10] LC_TELEPHONE=C       LC_MEASUREMENT=en_US LC_IDENTIFICATION=C 
## 
## attached base packages:
## [1] stats     graphics  grDevices utils     datasets  methods   base     
## 
## other attached packages:
## [1] emmeans_1.4.8    kableExtra_1.2.1 knitr_1.29       readxl_1.3.1    
## [5] rmarkdown_2.3    dplyr_1.0.0      ggplot2_3.3.5    edgeR_3.30.3    
## [9] limma_3.44.3    
## 
## loaded via a namespace (and not attached):
##  [1] zoo_1.8-8         tidyselect_1.1.0  locfit_1.5-9.4    xfun_0.16        
##  [5] purrr_0.3.4       splines_4.0.1     lattice_0.20-41   colorspace_1.4-1 
##  [9] vctrs_0.3.2       generics_0.0.2    htmltools_0.5.0   viridisLite_0.4.0
## [13] yaml_2.2.1        survival_3.2-3    rlang_0.4.11      pillar_1.4.6     
## [17] glue_1.4.1        withr_2.2.0       multcomp_1.4-13   lifecycle_0.2.0  
## [21] stringr_1.4.0     munsell_0.5.0     gtable_0.3.0      cellranger_1.1.0 
## [25] rvest_0.3.6       mvtnorm_1.1-1     codetools_0.2-16  evaluate_0.14    
## [29] labeling_0.3      highr_0.8         TH.data_1.0-10    Rcpp_1.0.5       
## [33] xtable_1.8-4      scales_1.1.1      webshot_0.5.2     farver_2.0.3     
## [37] digest_0.6.25     stringi_1.4.6     grid_4.0.1        tools_4.0.1      
## [41] sandwich_2.5-1    magrittr_1.5      tibble_3.0.3      crayon_1.3.4     
## [45] pkgconfig_2.0.3   MASS_7.3-51.6     ellipsis_0.3.1    Matrix_1.2-18    
## [49] xml2_1.3.2        estimability_1.3  httr_1.4.2        rstudioapi_0.11  
## [53] R6_2.4.1          compiler_4.0.1